WPI Symposium on Advanced Biomanufacturing Agenda

Worcester Polytechnic Institute 

4th Annual Advanced Biomanufacturing Symposium Archive

May 1, 2019 –  Advancements in Protein Therapeutics and Emerging Technologies

May 2, 2019 – Cell and Tissue Therapies

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May 1: Advancements in Protein Therapeutics & Emerging Technology

8:00 AM Breakfast and Networking
8:40 AM Welcoming Remarks

Jean King, PhD, Peterson Family Dean of Arts & Sciences, WPI

8:45 AM Opening Remarks 

Mike Kennealy, Secretary, Executive Office of Housing and Economic Development, Commonwealth of Massachusetts

9:00 AM Keynote: Establishing a Community to Address Challenges in Genome Scale Science and Biomanufacturing for Mammalian Cell Cultures

Michael J. Betenbaugh
Center Director, Advanced Mammalian Biomanufacturing Innovation Center  (AMBIC), Professor, Department of Chemical and Biomolecular Engineering, Johns Hopkins University

Keynote Introduction by: Joseph Duffy, PhD, Professor and Department Head, Biology & Biotechnology, WPI
9:45 AM Chairperson’s Remarks 

Bogdan Vernescu, PhD, Vice Provost for Research, WPI

9:50 AM Single Use Technology and Sustainability: Quantifying the Environment Impact

Patrick Guertin, Global Technical Manager, GE Life Sciences

10:20 AM Applied Systems & Synthetic Biology: Engineering Yeasts and CHO Cells for Biomanufacturing

Eric Young, PhD, Assistant Professor, Chemical Engineering, WPI

10:50 AM Break 
11:10 AM Enabling a Culture of Quality with Knowledge Management

Amy DoucetteAmericas Manager & Global Strategic Accounts, Applied Materials Pharma Group

11:40 AM Process Design Concepts for Hybrid and Single Use Technologies

Kevin Lynch, Head of Sales Integrated Solutions, Sartorius Stedim Biotech

12:10 PM Lunch Break 
1:10 PM Chairperson’s Remarks 

Reeta Rao, PhD, Professor, Biology & Biotechnology, WPI

1:15 PM An Evolution of Antibody Drug Conjugate Structure: Implications for Manufacturing

Leo Letendre, PhD, Research Fellow, Pfizer

1:45 PM Case Studies Illustrating Cell Culture Scale-Up Using Stirred-Tank Single Use Bioreactors

Michelet Dorceus, Senior Application Specialist, Eppendorf North America

2:15 PM Design of an Antibody-Drug Conjugate Facility: Balancing Function and Flexibility

Cynthia Wooge, PhD, Head of Process & Technology, MilliporeSigma

2:45 PM Break
3:05 PM Implementation of Protein A Multi-Column Chromatography at Process Scale

Denis Kole, PhD, SLS Manager – Continuous Bioprocessing US, Pall Biotech

3:35 PM Panel Discussion: Challenges in Implementing Automation in Biomanufacturing

Lou Mello, OEM Manager, Life Sciences, Rockwell Automation
Pam Obando, Principal Engineer, Global Supply, Pfizer Inc.

Panel Moderator: Susan Roberts, PhD, Professor and Department Head, Chemical Engineering, WPI 
4:35 PM Networking & Cocktail Reception

May 2: Gene, Cellular & Tissue Therapies

8:00 AM Breakfast and Networking
8:45 AM Keynote Introduction and Update by: Travis McCready, JD, President & CEO, Massachusetts Life Sciences Center
 9:00 AM Keynote: Drawing Creatively within the Lines: Regulatory Approaches for Emerging Regenerative Medicine Therapies

Richard D. McFarland, PhD, MD

Chief Regulatory Officer, Advanced Regenerative Manufacturing Institute (ARMI) | BioFabUSA

9:45 AM Chairperson’s Remarks

John McNeill, PhD, Dean of Engineering, WPI

9:50 AM Using Lipid Nanoparticles to Efficiently Deliver CRISPR/Cas9 for Genome Editing in Rodents and Non-Human Primates

Ramsey Majzoub, PhD, Senior Scientist, Intellia Therapeutics Inc.

10:20 AM GMP Production of Viral Vectors for Gene Therapy Applications

Alejandro Negrete, PhD, Manager, Technology Transfer, Viral and Gene Therapy Manufacturing Services, MilliporeSigma

10:50 AM Break
11:10 AM Incorporating Systems Biology into Commercial Biologics Manufacturing for Improved Cell Culture Performance

Amanda Lewis, PhD, Principal Engineer, Manufacturing Sciences & Technology, Bristol-Myers Squibb

11:40 AM Supporting Tissue Engineered Medical Product Translation through Manufacturing

Mary Clare McCorry, PhD, Director, Technology and Process Development, Advanced Regenerative Manufacturing Institute (ARMI)

12:10 PM Lunch Break
1:10 PM Chairperson’s Remarks

Kris Billiar, PhD, Department Head and Professor, Biomedical Engineering, WPI

1:15 PM Designing and 3D Printing Hydrogel Systems to Address Challenges in Biofabrication

Chris Highley, PhD, Assistant Professor, Biomedical Engineering, University of Virginia

1:45 PM Biomimetic Materials Support of Stem Cell Differentiation for Cardiovascular Regeneration

Elizabeth Lipke, PhD, Mary and John H. Sanders Associate Professor, Chemical Engineering, Auburn University

2:15 PM Break
2:35 PM Cancer Micro-Tissue Modeling for Increased Content, Throughput, and Predictability

Catherine F. Whittington, PhD, Assistant Professor, Biomedical Engineering, WPI
3:05 PM CAR T: Technology, Process and Validation

Mahezabin Tai & Omotola Saka, Technical Training, CAR-T Manufacturing Operations, Celgene

3:35 PM Concluding Remarks

Rachel LeBlanc. Assistant VP, Academic & Corporate Engagement, WPI

 

Schedule subject to change.