Projects
New journal articles from the MBL!
MBL member Joshua Johnson has two recent publications: 1. Validation of a new multiscale finite element analysis approach at the distal radius (Med. Eng. Phys) 2. Simplified boundary conditions alter cortical-trabecular load sharing at the distal radius; A multiscale finite element analysis. (J. Biomech) MBL Director Karen Troy just published an article on Practical considerations for […]
Femur fracture at high speed
Did you know that it takes less than 1/100th of a second for a crack to nucleate and propagate through bone when it is impacted? In collaboration with Dr. Nima Rahbar and his lab, we recently collected high-speed video of a femur as it fractured. We will use the data we collect to predict where […]
Measurement of bone deformity in Rheumatoid and Psoriatic Arthritis
Rheumatoid arthritis (RA) and Psoriatic Arthritis (PsA) are two types of chronic inflammatory arthritis that result in progressive disability and joint degeneration. RA results in abnormalities in bone metabolism, including the generation of focal bone erosion sites within joints and patients with PsA develop pathologic bone formations (osteophytes). The joints of the hand are commonly […]
Non-invasive measurement of bone
Bone adaptation is understood to be driven by mechanical stimuli that are related to bone strain. Logically, if bone strain is a driver of adaptation and osteogenic response, then knowing how human bone is strained in vivo during certain activities might help us to identify specific strategies that could be used to help people naturally […]
Bone Health after Spinal Cord Injury
Spinal cord injury (SCI) causes paralysis and as a result, the mechanical stimulation to the skeleton normally provided by muscle activity and weight bearing is severely attenuated. Bone loss is a prominent feature of the immediate post-injury period, however fracture rate does not increase significantly until 5-10 years post-injury. These features make individuals with SCI […]
Bone Adaptation in Healthy People
Healthy bone adapts to best resist its habitual mechanical loading environment. When the applied daily mechanical stimulus drops below some minimum threshold, bone loss occurs. Similarly, when the stimulus exceeds some threshold, bone will adapt to become stronger through a combination of increased bone mass and changes to bone geometry that are associated with increased […]
Musculoskeletal Biomechanics Laboratory Projects
Our research focus is on understanding how forces applied to the musculoskeletal system can influence bone and joint health and function in adult men and women in health and disease.
