(FY 04) Unraveling the Role of GABAergic Dysfunction in Catatonia: A GABAergic Investigation in Drosophila

Author: Varsha Alladi

Advisors: Kevin Crowthers

Category: First Year

Abstract:The overall aim of this project is to examine how GABAergic dysfunction affects sensory perception and motor activity using drosophila melanogaster as a model organism. The experiment will look at the effects of bicuculline, a GABA-A receptor antagonist, on behaviors like social clustering, chemosensory responsiveness, and locomotion. The disturbance of GABAergic neurotransmission is expected to result in detectable abnormalities in these behaviors, overall providing information into the neurobiological causes of catatonia

UN SDGs:

SDG 3 – Good Health and Well Being

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