Publications

  1. Gong J, Nirala NK, Chen J, Wang F, Gu P, Wen Q, Ip YT, Xiang Y. “TrpA1 is a shear stress mechanosensing channel regulating intestinal stem cell proliferation in Drosophila”.  Science Advances  2023 9 (21),eadc9660.
  2. Jebeli, M.; Lopez, S. K.; Goldblatt, Z. E.; McCollum, D.; Mana-Capelli, S.; Wen, Q.; Billiar, K. “Multicellular aligned bands disrupt global collective cell behavior”. Acta biomaterialia 2023 163 117-130.
  3. Gong, J.; Chen, J.; Gu, P.; Shang, Y.; Ruppell, K. T.; Yang, Y.; Wang, F.; Wen, Q.; Xiang, Y. “Shear stress activates nociceptors to drive Drosophila mechanical nociception”. Neuron 2022110 (22), 3727-3742.
  4. Zhou, Z.; Cui, F.; Wen, Q.; Susan Zhou, H. “Effect of vimentin on cell migration in collagen-coated microchannels: A mimetic physiological confined environment”. Biomicrofluidics 202115 (3), 034105.
  5. Ho Thanh, M. T.; Grella, A.; Kole, D.; Ambady, S.; Wen, Q. Vimentin intermediate filaments modulate cell traction force but not cell sensitivity to substrate stiffness. Cytoskeleton 202178 (6), 293-302.
  6. Zhu, P.; Hawkins, J.; Linthicum, W. H.; Wang, M.; Li, N.; Zhou, N.; Wen, Q.; Timme-Laragy, A.; Song, X.; Sun, Y. Heavy metal exposure leads to rapid changes in cellular biophysical properties. ACS Biomaterials Science & Engineering 20206 (4), 1965-1976.
  7. Ti, C.; Shen, Y.; Ho Thanh, M.-T.; Wen, Q.; Liu, Y. “Reliable and mobile all-fiber modular optical tweezers”. Scientific reports 202010 (1), 20099.
  8. Pearce, K. M.; Bell, M.; Linthicum, W. H.; Wen, Q.; Srinivasan, J.; Rangamani, P.; Scarlata, S. “Gαq-mediated calcium dynamics and membrane tension modulate neurite plasticity”. Molecular biology of the cell 202031 (7), 683-694.
  9. (8) Goldblatt, Z. E.; Choshali, H. A.; Cirka, H. A.; Liang, V.; Wen, Q.; McCollum, D.; Rahbar, N.; Billiar, K. L. “Heterogeneity profoundly alters emergent stress fields in constrained multicellular systems”. Biophysical journal 2020118 (1), 15-25.
  10. Cui, F.; Jafarishad, H.; Zhou, Z.; Chen, J.; Shao, J.; Wen, Q.; Liu, Y.; Zhou, H. S. “Batch fabrication of electrochemical sensors on a glycol-modified polyethylene terephthalate-based microfluidic device”. Biosensors and Bioelectronics 2020167, 112521.
  11. Wang, K.; Shi, L.; Linthicum, W.; Man, K.; He, X.; Wen, Q.; Rojanasakul, L. W.; Rojanasakul, Y.; Yang, Y. “Substrate stiffness-dependent carbon nanotube-induced lung fibrogenesis”. Nano letters 201919 (8), 5443-5451.
  12. Shendi, D.; Marzi, J.; Linthicum, W.; Rickards, A.; Dolivo, D.; Keller, S.; Kauss, M.; Wen, Q.; McDevitt, T.; Dominko, T. “Hyaluronic acid as a macromolecular crowding agent for production of cell-derived matrices”. Acta biomaterialia 2019100, 292-305.
  13. Ti, C.; Thanh, M.-T. H.; Shen, Y.; Wen, Q.; Liu, Y. “Fiber Optical Tweezers for Applying and Measuring Forces in a 3D Solid Compartment”. In Selected Topics on Optical Fiber Technologies and Applications, IntechOpen, 2018.
  14. Neumann, B. M.; Kenney, D.; Wen, Q.; Gericke, A. “Microfluidic device as a facile in vitro tool to generate and investigate lipid gradients”. Chem Phys Lipids 2018210, 109-121. DOI: 10.1016/j.chemphyslip.2017.10.007  From NLM Medline.
  15. Linthicum, W.; Thanh, M.-T. H.; Vitolo, M. I.; Wen, Q. “Effects of PTEN loss and activated KRAS overexpression on mechanical properties of breast epithelial cells”. International journal of molecular sciences 201819 (6), 1613.
  16. Wang, K.; He, X.; Linthicum, W.; Mezan, R.; Wang, L.; Rojanasakul, Y.; Wen, Q.; Yang, Y. “Carbon nanotubes induced fibrogenesis on nanostructured substrates”. Environmental Science-Nano 20174 (3), 689-699. DOI: 10.1039/c6en00402d.
  17. Ti, C.; Ho-Thanh, M.-T.; Wen, Q.; Liu, Y. “Objective-lens-free fiber-based position detection with nanometer resolution in a fiber optical trapping system”. Scientific reports 20177 (1), 13168.
  18. Ning, D.; Duong, B.; Thomas, G.; Qiao, Y.; Ma, L.; Wen, Q.; Su, M. “Mechanical and Morphological Analysis of Cancer Cells on Nanostructured Substrates”. Langmuir 201632 (11), 2718-2723. DOI: 10.1021/acs.langmuir.5b04469.
  19. Cirka, H.; Monterosso, M.; Diamantides, N.; Favreau, J.; Wen, Q.; Billiar, K. “Active Traction Force Response to Long-Term Cyclic Stretch Is Dependent on Cell Pre-stress”. Biophysical journal 2016110 (8), 1845-1857. DOI: 10.1016/j.bpj.2016.02.036.
  20. Beliveau, A.; Thomas, G.; Gong, J.; Wen, Q.; Jain, A. “Aligned Nanotopography Promotes a Migratory State in Glioblastoma Multiforme Tumor Cells”. Scientific reports 20166. DOI: 10.1038/srep26143.
  21. Ti, C.; Thomas, G. M.; Ren, Y.; Zhang, R.; Wen, Q.; Liu, Y. “Fiber based optical tweezers for simultaneous in situ force exertion and measurements in a 3D polyacrylamide gel compartment”. Biomedical Optics Express 20156 (7), 2325-2336. DOI: 10.1364/BOE.6.002325.
  22. Stanton, M. M.; Parrillo, A.; Thomas, G. M.; McGimpsey, W. G.; Wen, Q.; Bellin, R. M.; Lambert, C. R. “Fibroblast extracellular matrix and adhesion on microtextured polydimethylsiloxane scaffolds”. Journal of Biomedical Materials Research Part B: Applied Biomaterials 2015103 (4), 861-869.
  23. Janmey, P. A.; Slochower, D. R.; Wang, Y.-H.; Wen, Q.; Cebers, A. “Polyelectrolyte properties of filamentous biopolymers and their consequences in biological fluids”. Soft matter 201410 (10), 1439-1449. DOI: 10.1039/c3sm50854d.
  24. El Assal, R.; Guven, S.; Gurkan, U. A.; Gozen, I.; Shafiee, H.; Dalbeyler, S.; Abdalla, N.; Thomas, G.; Fuld, W.; Illigens, B. M. “Bio‐inspired cryo‐ink preserves red blood cell phenotype and function during nanoliter vitrification”. Advanced materials 201426 (33), 5815-5822.
  25. Wen, Q.; Janmey, P. A. “Effects of non-linearity on cell–ECM interactions”. Experimental cell research 2013319 (16), 2481-2489.
  26. Thomas, G.; Burnham, N. A.; Camesano, T. A.; Wen, Q. “Measuring the mechanical properties of living cells using atomic force microscopy”. JoVE (Journal of Visualized Experiments) 2013,  (76), e50497.
  27. Rudnicki, M. S.; Cirka, H. A.; Aghvami, M.; Sander, E. A.; Wen, Q.; Billiar, K. L. “Nonlinear Strain Stiffening Is Not Sufficient to Explain How Far Cells Can Feel on Fibrous Protein Gels”. Biophysical journal 2013105 (1), 11-20. DOI: 10.1016/j.bpj.2013.05.032.
  28. Wen, Q.; Basu, A.; Janmey, P. A.; Yodh, A. G. “Non-affine deformations in polymer hydrogels”. Soft matter 20128 (31), 8039-8049. DOI: 10.1039/c2sm25364j.
  29. Tang, X.; Wen, Q.; Kuhlenschmidt, T. B.; Kuhlenschmidt, M. S.; Janmey, P. A.; Saif, T. A. “Attenuation of Cell Mechanosensitivity in Colon Cancer Cells during In Vitro Metastasis”. Plos One 20127 (11). DOI: 10.1371/journal.pone.0050443.
  30. Davis, J. T.; Wen, Q.; Janmey, P. A.; Otteson, D. C.; Foster, W. J. “Müller cell expression of genes implicated in proliferative vitreoretinopathy is influenced by substrate elastic modulus”. Investigative ophthalmology & visual science 201253 (6), 3014-3019.
  31. Wen, Q.; Janmey, P. A. “Polymer physics of the cytoskeleton”. Current opinion in solid state & materials science 201115 (5), 177-182. DOI: 10.1016/j.cossms.2011.05.002.
  32. Huisman, E. M.; Wen, Q.; Wang, Y.-H.; Cruz, K.; Kitenbergs, G.; Ērglis, K.; Zeltinš, A.; Cēbers, A.; Janmey, P. A. “Gelation of semiflexible polyelectrolytes by multivalent counterions”. Soft matter 20117 (16), 7257-7261.
  33. Byfield, F. J.; Wen, Q.; Leszczynska, K.; Kułakowska, A.; Namiot, Z.; Janmey, P. A.; Bucki, R. “Cathelicidin LL-37 peptide regulates endothelial cell stiffness and endothelial barrier permeability”. Am J Physiol-Cell Ph 2011300 (1), C105-C112.
  34. Basu, A.; Wen, Q.; Mao, X.; Lubensky, T. C.; Janmey, P. A.; Yodh, A. G. “Nonaffine Displacements in Flexible Polymer Networks”. Macromolecules 201144 (6), 1671-1679. DOI: 10.1021/ma1026803.
  35. Kułakowska, A.; Ciccarelli, N. J.; Wen, Q.; Mroczko, B.; Drozdowski, W.; Szmitkowski, M.; Janmey, P. A.; Bucki, R. “Hypogelsolinemia, a disorder of the extracellular actin scavenger system, in patients with multiple sclerosis”. BMC neurology 201010, 1-8.
  36. Foster, W.; Davis, J.; Wen, Q.; Lam, P.; Otteson, D.; Janmey, P. “Substrate Stiffness Influences Müller Cell Morphology, Proliferation, and the Expression of Genes That Are Known to Play a Role in Proliferative Vitreoretinopathy”. Investigative ophthalmology & visual science 201051 (13), 6090-6090.
  37. Chen, D. T. N.; Wen, Q.; Janmey, P. A.; Crocker, J. C.; Yodh, A. G. “Rheology of Soft Materials”. In Annual Review of Condensed Matter Physics, Vol 1, Vol. 1; 2010; pp 301-322.
  38. Leszczyńska, K.; Namiot, A.; Fein, D. E.; Wen, Q.; Namiot, Z.; Savage, P. B.; Diamond, S.; Janmey, P. A.; Bucki, R. “Bactericidal activities of the cationic steroid CSA-13 and the cathelicidin peptide LL-37 against Helicobacter pylori in simulated gastric juice”. BMC microbiology 20099, 1-10.
  39. Kang, H.; Wen, Q.; Janmey, P. A.; Tang, J. X.; Conti, E.; MacKintosh, F. C. “Nonlinear elasticity of stiff filament networks: strain stiffening, negative normal stress, and filament alignment in fibrin gels”. The Journal of Physical Chemistry B 2009113 (12), 3799-3805.
  40. Janmey, P. A.; Winer, J. P.; Murray, M. E.; Wen, Q. “The Hard Life of Soft Cells”. Cell Motility and the Cytoskeleton 200966 (8), 597-605. DOI: 10.1002/cm.20382.
  41. Byfield, F. J.; Wen, Q.; Levental, I.; Nordstrom, K.; Arratia, P. E.; Miller, R. T.; Janmey, P. A. “Absence of Filamin A Prevents Cells from Responding to Stiffness Gradients on Gels Coated with Collagen but not Fibronectin”. Biophysical journal 200996 (12), 5095-5102. DOI: 10.1016/j.bpj.2009.03.046.
  42. Wen, Q.; Li, G.; Tang, J. X.; Huber, G. “Switching statistics of a flagellar motor: First-passage time and dynamic binding”. Journal of Statistical Physics 2007128 (1-2), 257-267. DOI: 10.1007/s10955-006-9249-x.
  43. Wen, Q.; Basu, A.; Winer, J. P.; Yodh, A.; Janmey, P. A. “Local and global deformations in a strain-stiffening fibrin gel”. New J Phys 20079 (11), 428.
  44. Wagner, O. I.; Rammensee, S.; Korde, N.; Wen, Q.; Leterrier, J.-F.; Janmey, P. A. “Softness, strength and self-repair in intermediate filament networks”. Experimental cell research 2007313 (10), 2228-2235. DOI: 10.1016/j.yexcr.2007.04.025.
  45. Ērglis, K.; Wen, Q.; Ose, V.; Zeltins, A.; Sharipo, A.; Janmey, P. A.; Cēbers, A. “Dynamics of magnetotactic bacteria in a rotating magnetic field”. Biophysical journal 200793 (4), 1402-1412.
  46. Wen, Q.; Tang, J. X. “Temperature effects on threshold counterion concentration to induce aggregation of fd virus”. Physical Review Letters 200697 (4). DOI: 10.1103/PhysRevLett.97.048101.
  47. Tang, J. X.; Wen, Q.; Bennett, A.; Kim, B.; Sheils, C. A.; Bucki, R.; Janmey, P. A. “Anionic poly (amino acid) s dissolve F-actin and DNA bundles, enhance DNase activity, and reduce the viscosity of cystic fibrosis sputum”. American Journal of Physiology-Lung Cellular and Molecular Physiology 2005289 (4), L599-L605.
  48. Li, G.; Wen, Q.; Tang, J. X. “Single filament electrophoresis of F-actin and filamentous virus fd”. The Journal of chemical physics 2005122 (10), 104708. DOI: 10.1063/1.1859284.
  49. Wen, Q.; Tang, J. “Absence of charge inversion on rodlike polyelectrolytes with excess divalent counterions”. Journal of Chemical Physics 2004121 (24), 12666-12670. DOI: 10.1063/1.1822912.