Publications

Peer-Reviewed Research or Review Articles Published or in press (since joining WPI in January 2018)

Citations are organized in reverse chronological order. WPI undergraduates or Mass Academy student in italics, WPI graduate students underlined. Asterisks (*) indicate non-WPI undergraduates (i.e., NSF REU students).

  • Jones, A.E., Netto, J.F., Foote, T.L., Ruliffson, B.N.K., Whittington, C.F. Combined effects of matrix stiffness and obesity-associated signaling directs progressive phenotype in PANC-1 pancreatic cancer cells in vitro. Submitted to BIORXIV (awaiting DOI). 2024.
  • Ruliffson, B. N. K., Larson, S.M., Xhupi, E.L., Herrera-Diaz, D.L.*, Whittington, C. F., Characterization of photo-crosslinked methacrylated type I collagen as a platform to investigate lymphatic endothelial cell response. DOI: 10.20944/preprints202406.0727.v1.
  • Samolyk, B.L., Pace, Z.Y., Li, J., Billiar, K.L., Coburn, J.M., Whittington, C.F., Pins, G.D. Developing Porous Fibrin Scaffolds with Tunable Anisotropic Features that Direct Myoblast Orientation. Tissue Engineering Part C: Methods, 30(5): 217-228, 2024.
  • Ruliffson, B. N. K., Whittington, C. F., Regulating Lymphatic Vasculature in Fibrosis: Understanding the Biology to Improve the Modeling. Advanced Biology, 7(5):e2200158, 2023.

Peer-Reviewed Research or Review Articles Published or in press (from training prior to joining WPI )

  • Liu, J., Cho, Y.B., Hong, H.K., Wu, S., Ebert, P., Bray, S., Wong, S., Ting, J., Calley, J., Whittington, C.F., Bhagwat, S.V., Reinhard, C., Wild, R., Nam, D.H., Aggarwal, A., Lee, W.Y., Peng, S. Molecular Dissection of CRC Primary Tumors and Their Matched Liver Metastases Reveals Critical Role of Immunosuppression, EMT, and Angiogenesis in Cancer Metastasis. Scientific Reports 10, 10725, 2020.
  • Puls, T.J., Tan, X., Husain, M., Whittington, C.F., Fishel, M.L., Voytik-Harbin, S.L. Development of a Novel 3D Tumor-Tissue Invasion Model for High-throughput, High-content Phenotypic Drug Screening. Scientific Reports, 8(1): 13039, 2018.
  • Puls, T.J., Tan, X., Whittington, C.F., Voytik-Harbin, S.L. 3D collagen fibrillar microstructure guides pancreatic cancer cell phenotype and serves as a critical design parameter for phenotypic models of EMT. PloS One, 1 2(11): e0188870, 2017.
  • Park, S.M., Whittington, C., Voytik-Harbin, S.L., Han, B. Microstructural parameter-based modeling for transport properties of collagen matrices. Journal of Biomechanical Engineering, 137(6): epub, Paper No: BIO-14-1479; doi: 10.1115/1.4029920, 2015.
  • Richardson, M.R., Robbins, E.P., Vemula, S., Critser, P.J., Whittington, C., Voytik-Harbin, S.L., Yoder, M.C. Angiopoietin-like protein 2 regulates endothelial colony forming cell vasculogenesis. Angiogenesis, 7(3):675-83, 2014.
  • Whittington, C.F., Yoder, M.C., Voytik-Harbin, S.L. Collagen-Polymer Guidance of Vessel Network Formation and Stabilization by Endothelial Colony Forming Cells In Vitro. Macromolecular Bioscience, 13(9): 1135-1149, 2013.
  • Whittington, C.F., Brandner, E., Teo, K.Y., Han, B., Nauman, E., Voytik-Harbin, S.L. Oligomers Modulate Interfibril Branching and Mass Transport Properties of Collagen Matrices. Microscopy and Microanalysis, 19(5): 1323-1333, 2013.
  • Monteleon, C.L., Sedgwick, A., Hartsell, A., Dai, M., Whittington, C., Voytik-Harbin, S., D’Souza-Schorey, C. Establishing epithelial glandular polarity: interlinked roles for ARF6, Rac1, and the matrix microenvironment. Mol. Biol. Cell, 23(23): 4495-4505, 2012.
  • Bailey, J. L., Critser, P. J., Whittington, C., Kuske, J. L., Yoder, M. C., Voytik-Harbin, S. L. Collagen oligomers modulate physical and biological properties of three-dimensional self-assembled matrices. Biopolymers, 95(2): 77-93, 2011.
  • Zhong, Y., Whittington, C.F., Zhang, L. and Haynie, D.T. Controlled loading and release of a model drug from polypeptide multilayer nanofilms. Nanomedicine, 3(2):154-160, 2007.
  • Zhong, Y., Whittington, C.F. and Haynie, D.T. Stimulated release of small molecules from polyelectrolyte multilayer nanocoatings Chemical Communications, (14):15-1417, 2007.

Refereed Conference Proceedings (from training prior to January 2018)

  • Liu, J., et al. (2017) Molecular characterization of primary tumor & the paired liver metastatic biopsies of colorectal cancer reveals a critical role of immunosuppression, EMT & angiogenesis in cancer metastasis. AACR Annual Meeting. Cancer Research 77 (13_Supplement), 849-849.
  • Puls, T.J., Tan, X., Whittington, C.F., Voytik-Harbin, S.L. (2016) Novel 3D tumor-stromal model highlights the importance of ECM composition and biophysical properties in pancreatic cancer EMT and drug resistance. AACR Special Conference: Engineering and Physical Sciences in Oncology. Cancer Res (2017) 77 (2_Supplement): A57.
  • Park, S., Whittington, C., Yoder, M.C., Voytik-Harbin, S.L., Han, B. (2012). Effects of Collagen Microstructure on the Transport Properties of Vascularized Engineered Tissues. Proceedings of ASME 2012 Summer Bioengineering Conference, SBC2012-80817, 44809, pp. 633-634.