Lab News

Congratulations to Daniel Zimmer on a successful research proposition!

December 13, 2023. Daniel did a great job and passed his research proposition, advancing him to a PhD Candidate in Chemical Engineering!

Bailey-Hytholt Lab Holiday Party

December 11, 2023. We had lots of fun celebrating the holidays together!

Kerstin and Elizaveta present their undergraduate summer research at the Women’s Impact Network Fall 2023 Retreat

November 10, 2023. Check out the WIN retreat schedule here. Great job Kerstin and Elizaveta!

 

Kerstin Andrews presents “Characterizing trophoblast extracellular vesicles for pre-eclamptic protein analysis.”

 

Elizaveta Tcherniaeva presents “Investigating the physicochemical properties of nucleic acid loaded lipid nanoparticles.”

Lexi Harrison participates in the NextProf Pathfinder Workshop!

October 22-24, 2023. Congratulations, Lexi!

Congratulations to undergraduate researcher, Warren Callen, on being named a 2023 Future Leader in Chemical Engineering by NC State University

October 22-23, 2023. We are very proud of Warren! Learn more here. 

Warren presenting his research at the Future Leaders in Chemical Engineering conference:

Lexi Harrison and Daniel Zimmer present at Nature Conference – Cracking the Code: The Dawn of Nucleic Acid Medicines

October 17-19, 2023

Lexi Harrison presents on “Ionizable lipid content of messenger RNA loaded lipid nanoparticles impact delivery and gene expression in trophoblast cells.”

Daniel Zimmer presents on “Electrophoresis Microfluidic Assessment of Nucleic Acid Loading in Lipid Nanoparticles.”

Prof. Bailey-Hytholt named to 2023 Extraordinary Women Advancing Healthcare award

October 2023. Prof. Bailey-Hytholt was selected for the Extraordinary Women Advancing Healthcare award from The Women’s Edge (Formerly The Commonwealth Institute). Check out WPI’s announcement here.

Christina Bailey-Hytholt

Prof. Bailey-Hytholt awarded American Institute for Chemical Engineers (AIChE) 35 under 35

October 2023. Prof. Bailey-Hytholt was selected for the AIChE 35 under 35 award. Bailey-Hytholt is one of six awardees in the Bioengineering category, recognized for her impactful work on developing new biomaterials and drug delivery vehicles influencing fundamental understanding and treatment strategies for reproductive health complications. AIChE has been an instrumental professional home for Bailey-Hytholt throughout each stage of her career.

AIChE 35 Under 35 Award

PhD student, Lexi Harrison, and undergraduate researcher, Warren Callen, present at New England Complex Fluids

September 22, 2023. Lexi Harrison presents her work “Ionizable lipid content of messenger RNA loaded lipid nanoparticles impacts delivery and gene expression in trophoblast cells” and Warren Callen presents his work “Using lipophilic dyes to examine lipid nanoparticle structure” at the New England Complex Fluids Workshop hosted by Brandeis University. They did a great job!

      

Congratulations to Lexi Harrison for being accepted into the NextProf Pathfinder Workshop!

September 2023. PhD student Lexi Harrison will be participating in a 2-day workshop at University of Michigan in collaboration with Georgia Institute of Technology and University of California San Diego. “The NextProf Pathfinder Workshop is intended for rising 1st and 2nd year PhD students and those in a Master’s program intending to apply for a PhD program. The workshop prepares participants for a successful career in academia, and offers information on what it takes to build a competitive graduate school record to obtain a faculty position in academia/the professoriate. An ideal NextProf Pathfinder candidate will express a passion for teaching and interest in making engineering academia a more inclusive and rewarding experience for all students, and has a desire to positively influence institutional conversations about diversity.” 

Congratulations to Daniel Zimmer for being accepted into the StartUp Worcester program!

August 29, 2023. PhD student Daniel Zimmer has been accepted to participate in the StartUp Worcester program, an accelerator program run by the Venture Forum, The Worcester Chamber of Commerce, and the Score mentorship program. Learn more about it here!

 

 

End of summer lab group lunch

August 2023. Celebrating a fun and productive summer of research!

 

Bailey-Hytholt Lab undergraduate researchers present at the 2023 WPI Summer Research Showcase

August 3, 2023. Congratulations to all of our summer undergraduate researchers!

Elizaveta Tcherniaeva

Investigating the physicochemical properties of nucleic acid loaded lipid nanoparticles

Elizaveta participated in WPI’s Early Research Experience in E-Term (EREE) program. As an undergraduate researcher, during the summer she formulated and assessed three different lipid nanoparticle formulations.

Adelyn Fisher

Evaluating Cell Viability After Treatment with Lipid Nanoparticles

Adelyn is an undergraduate researcher, evaluating cell viability of  trophoblast cells with various lipid-based treatments.

Kerstin Andrews

Characterizing trophoblast extracellular vesicles for pre-eclampsia protein analysis

Kerstin participated in WPI’s Early Research Experience in E-Term (EREE) program. As an undergraduate researcher, Kerstin investigates trophoblast secreted extracellular vesicles.

Anna Gwozdz

Examining Lipid Nanoparticle Formulation Dependence on Messenger RNA Delivery to Trophoblast Cells

Anna participated in a National Science Foundation funded Research Experience for Undergraduates (REU) program. Her summer research focused on the delivery of mRNA loaded lipid nanoparticles to placental cells to help treat pregnancy-related. complications. Anna will be a senior undergraduate student at Alfred University in Fall 2023, and we wish her all the best!

Daniel Zimmer presents at RICT 2023 – 57th International Conference on Medicinal Chemistry

July 5 – 7, 2023. PhD student Daniel Zimmer presents at the RICT 2023 meeting on his work titled: “Development and application of cell-free proteoliposome vesicles to assess molecular transport across the placenta.”

Bailey-Hytholt Lab BBQ!

June 24, 2023. Great time at our annual summer lab BBQ!

Bailey-Hytholt Lab attends the ACS Northeast Regional Meeting

June 14-17, 2023. PhD student Daniel Zimmer presents his work at the 2023 ACS NERM meeting: “Assessment of lipid nanoparticles: Developing a method to quantify encapsulated nucleic acid per particle.” Great job, Daniel!

Bailey-Hytholt Lab graduate and undergraduate researchers attend the meeting.

 

Congratulations to Bailey-Hytholt Lab MS student Yihui Chen on graduating from WPI ChE!

May 12, 2023. Congratulations to Yihui and we wish him all the best as he starts as a PhD student at the University at Buffalo in the Fall!

Bailey-Hytholt Lab senior undergraduate researchers present their Major Qualifying Projects at the Undergraduate Research Projects Showcase

April 21, 2023. Congratulations to our senior undergraduate research teams for doing a fantastic job presenting their work!

 Michela Benazzi & Matthew Shea

“Lipid nanoparticle uptake and exosome isolation in trophoblast cells”

Julia Afthim, Dylan Rapoport, Wasef Raza

“Encapsulating and characterizing bacteriophage loaded in liposomes”

Congratulations to Julia, Dylan, and Wasef for receiving 3rd place in the Chemical Engineering poster competition!

PhD student Daniel Zimmer presents at 2023 BMES Advanced Biomanufacturing (ABioM) Meeting

March 22-24, 2023. Daniel presents his Massachusetts Life Science Center funded work titled “Developing a biomimetic model of placental drug transport” at the 2023 ABioM meeting in Hyattsville, MD. Great work!

PhD student Daniel Zimmer presents at WPI’s Graduate Research Innovation Exchange

February 8, 2023. Daniel Zimmer presenting his research on “Cell-Free Assessment of Placental Drug Transport” at WPI’s Graduate Research Innovation Exchange (GRIE).

Eleni presents at the 2022 WPI Summer Research Showcase

August 4, 2022. Eleni Xhupi participated in WPI’s Early Research Experience in E-Term (EREE) program and presented her work titled “Biomimetic Drug Delivery using Lipid Nanoparticles and Exosomes.” Great job, Eleni!

Prof. Bailey-Hytholt and PhD student Daniel Zimmer present at AIChE

November 28, 2022. Prof. Bailey-Hytholt gives an invited talk on “Lipid-based systems: From therapeutics to in vitro models” in the Micro- and Nano-Scale Technologies in Life Sciences I session at AIChE on November 16, 2022. Prof. Bailey-Hytholt’s abstract

Daniel Zimmer, a 2nd year PhD student in the lab, presents on “Proteoliposome Development for Placental Biomimetic Models” in the Biomimetic Materials II session at the American Institute for Chemical Engineers (AIChE) Annual Meeting in Phoenix, Arizona on November 15, 2022. Check out his abstract here: Daniel’s AIChE Abstract

Welcome to the lab, Lexi Harrison!

October 2022. Lexi Harrison, Ph.D. student in Chemical Engineering, joins the lab! Welcome to our research team!

Prof. Bailey-Hytholt presents at the 92nd New England Complex Fluids meeting

September 23, 2022. Prof. Bailey-Hytholt gives an invited research talk at the 92nd New England Complex Fluids meeting at Brandies University. See the schedule here.

Dr. Bailey-Hytholt gives seminar talk for DEVCOM Soldier Center

April 14, 2022. Prof. Bailey-Hytholt gives a seminar talk titled “Lipid-based systems: From therapeutics to in vitro models” at the DEVCOM Soldier Center COVID-19 Virtual Seminar Series.

Prof. Bailey-Hytholt is named to Forbes’ 30 under 30 Science list!

January 2022. 

Read more about Prof. Bailey-Hytholt here!

And view the list of all the 2022 honorees here!

Welcome to the lab, Daniel Zimmer!

January 2022. Daniel Zimmer joins the lab as our first Ph.D. student! Welcome to the research team!

Our lab receives funding support from the Massachusetts Life Sciences Center

January 2022. The Bailey-Hytholt lab receives funding support from the Massachusetts Life Sciences Center Women’s Health Innovation Grant Program to increase understanding of maternal-fetal interface through lipid-based models. Read more about the initiative and awardees here: https://www.masslifesciences.com/life-sciences-center-taking-lead-on-womens-health-initiative/

The Bailey-Hytholt Lab is starting up!

January 2022. The Bailey-Hytholt Lab is officially part of the Life Sciences and Bioengineering Center at WPI!