The Billiar lab works to understand how mechanical forces affect the cells living in the body’s soft tissues. Soft tissues of the body experience forces during exercise (muscles contract and pull on tendons and ligaments) and at rest (blood vessels stretch with each heartbeat, digestive organs stretch and contract during eating). A better understanding of how a cells “feel” forces, interpret these stimuli, and alter their behavior will aid in creating treatments, and even curing, of a number of diseases from heart valve disease to cancer.