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Free Workshop: Integrated Solutions for Effective Process Development
Join us for a free half day workshop in Worcester, MA at WPI’s Biomanufacturing Education and Training Center to learn how to implement more effective DoE and data integration in your bioprocess.
Biomanufacturing Education & Training Center at WPI and Applikon Biotechnology
DATE & TIME
Thursday, July 18th, 2019
Registration at 9:30 AM
Workshop at 10:00 AM – 3:00 PM, with complimentary lunch
Rotation through hands-on stations in the afternoon
WPI Gateway Park, 50 Prescott St, Worcester, MA 01605
MAP LINK: https://goo.gl/maps/3TFLmPrbEbJQKpRF6
Keynote speaker: Philip Ramsey, Principal Lecturer at University of New Hampshire & Owner of North Haven Group
Quality by Design initiatives strongly promote the use of designed experiments for process development and characterization. In this talk, we will see some of the new innovative types of experimental designs, how to properly use and analyze them, and how to use the results of the experiments to determine key input variables, assess the sensitivity of the responses to those inputs, and find robust operating conditions using optimization and simulation techniques.
Ask the Experts: Product Specialists will be on hand to share their knowledge with you on additional topics in this casual and collaborative workshop.
Imko Gaastra, Product Manager, Applikon Biotechnology BV
Recent developments have improved biologics tech transfer and validation through a common process control platform – applicable from discovery to production. Applikon’s V-Control combines DeltaV Discovery and Emerson’s PK Controller DeltaV to perform these tasks. By using an open architecture with no locked code, V-Control gives users full access to the control logic thus enabling users to access all the capabilities of DeltaV. Applications of V-control at the bench scale (250 mL-20 L) will be described.
George Barringer, Product Manager, Applikon Biotechnology, Inc.
The micro-Matrix is a compact 24 microreactor instrument. Full independent, programmable closed loop control of pH, dO, temperature, and agitation rate is standard. This technology is optimized for screening, DoE, and other applications in microbial, mammalian, and advanced cell and gene therapy in early to late stage process development. Applications in microbial and mammalian systems will be discussed.
John Sullivan, VP of Global Sales, Flownamics Analytical
Autosampling facilitates more frequent data from offline analyzers that are commonly being used with today’s bioreactors. Reducing risk of operator error in sampling and data processing provides a stress free solution. Learn about a seamless solution with Flownamics Segflow connected to an Applikon bioreactor system using Lucullus Process Information Management Software.
Ann D’Ambruoso, Mgr Product Management, Applikon Biotechnology Inc.
AppliFlex ST is a novel single-use stirred tank mini bioreactor. Single-use bioreactors in all scales are now commonplace in industry. The advantages of single-use sterility, lower infrastructure costs, smaller controlled facility requirements, and faster turnaround times are driving this trend. The Appliflex ST further advances the single-use technology by offering the user the opportunity to design a purpose built headplate, impeller and sparger design to fit their exact requirements. In addition the Appliflex ST is unique among SUBs in having a removable headplate. Applications of the Appliflex ST in microbial, mammalian, and advanced therapies will be discussed focusing on the design decisions which optimize the vessel for each area of use.
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