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Highlighted Preprint
  1. S. Gao, H. Ashikaga, M. Suzuki, T. Mansi, Y-H Kim, F-C Ghesu, J. Kang, E. M. Boctor, H. R. Halperin, H. K. Zhang, “Cardiac-Gated Spectroscopic Photoacoustic Imaging for Ablation-Induced Necrotic Lesion Visualization: In Vivo Demonstration in a Beating Heart”, bioRxiv 2022.05.23.492682; doi:


Journal Articles
  1. Y. Tang, R. Tsumura, A. Malik, J. Kaminski, H. K. Zhang, “Actuated Reflector-Based Three-Dimensional Ultrasound Imaging with Adaptive-Delay Synthetic Aperture Focusing”, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, in press.
  2. [Y. Wu, J. Kang], W. G. Lesniak, A. Lisok, H. K. Zhang, R. H. Taylor, [M. G. Pomper, E. M. Boctor], “System-level optimization in spectroscopic photoacoustic imaging of prostate cancer”, Photoacoustics, 27, 100378, 2022.
Conference Proceedings
  1. K. Bimbraw, C. J. Nycz, M. J. Schueler, Z. Zhang and H. K. Zhang, “Prediction of Metacarpophalangeal Joint Angles and Classification of Hand Configurations Based on Ultrasound Imaging of the Forearm”, IEEE ICRA, 2022.
  2. [Y. Tang, I. Abouaf, A. Malik], A. B. Gonzalez, A. Mishra, R. Tsumura, J. T. Kaminski, I. Sorokin, H. K. Zhang, “Mirror-Integrated Ultrasound Image-Guided Needle Intervention”, Proc. SPIE, SPIE Medical Imaging, 2022, Best Poster Award, Image-Guided Procedures, Robotic Interventions, and Modeling
  3. X. Ma, M. Moradi, H. Mustafa, M. Hunter, [Y. Chen, H. K. Zhang], “Feasibility of Robotic-Assisted Optical Coherence Tomography for 3D Scanning Area Expansion” Proc. SPIE, SPIE Photonics West, 2022.
  4. S. Gao, M. C. Flegal, H. K. Zhang, “Feasibility of Laparoscopic Photoacoustic Imaging System Based on Diffusing Side-Illumination Fibers”, Proc. SPIE, SPIE Photonics West, 2022.


Journal Articles
  1. S. Gao, R. Tsumura, D. P. Vang, K. Bisland, K. Xu, Y. Tsunoi, H. K. Zhang, “Acoustic-resolution photoacoustic microscope based on compact and low-cost delta configuration actuator” in Ultrasonics, 118, 106549, 2021.
  2. R. Tsumura, J. W. Hardin, K. Bimbraw, O. S. Odusanya, Y. Zheng, J. C. Hill, B. Hoffmann, W. Soboyejo, H. K. Zhang, “Tele-operative Robotic Lung Ultrasound Scanning Platform for Triage of COVID-19 Patients”, IEEE RA-L (accepted), 2021.
Conference Proceedings
  1. X. Ma, Z. Zhang, H. K. Zhang, “Autonomous Scanning Target Localization for Robotic Lung Ultrasound Imaging”, IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2021), 2021.
  2. Z. Zhang, Y. Yue, G. Wu, Y. Li, H. Zhang, “SBO-RNN: Reformulating Recurrent Neural Networks via Stochastic Bilevel Optimization”, Proceeding of Advances in Neural Information Processing Systems (NeurIPS), 2021.
  3. S. Gao, H. Ashikaga, T. Mansi, H. Halperin, H. K. Zhang, “Photoacoustic Necrotic Region Mapping for RF Ablation Guidance”, IEEE International Ultrasonic Symposium, 2021.
  4. S. M. Ravishankar, R. Tsumura, J. W. Hardin, B. Hoffmann, Z. Zhang, H. K. Zhang, “Anatomical Feature-Based Lung Ultrasound Image Quality Assessment Using Deep Convolutional Neural Network”, IEEE International Ultrasonic Symposium, 2021.
  5. [Shang Gao, Zhaoyuan Ma], Ryosuke Tsumura, Loris Fichera, Haichong K. Zhang, “Augmented Immersive Telemedicine through Camera View Manipulation Controlled by Head Motions”, SPIE Medical Imaging, 2021. (Oral)
  6. [Yichuan Tang, Vanshika Rohera], Mattew Bruno, Lianne Ureneck, Marilyn E. Gladamez, Marsha W. Rolle, Haichong K. Zhang, “Ultrasound Tomography Based TEBV Growth Monitoring: A Feasibility Study”, SPIE Medical Imaging, 2021. (Oral)
  7. Yichuan Tang, Aditya Malik, Haichong K. Zhang, “Acoustic Reflector-Based Three-dimensional Ultrasound Imaging”, SPIE Medical Imaging, 2021. (Poster)
Conference Abstracts
  1. H. K. Zhang, “Needle-aligned ultrasound imaging for percutaneous intervention”, IEEE ISMR Workshop, 2021.
  2. S. Gao, H. Ashikaga, T. Mansi, H. Halperin, H. K. Zhang, “Feasibility of photoacoustic-based intraoperative necrotic region visualization for image guided catheter RF ablation”, IEEE International Ultrasonic Symposium, 2021.


Book Chapters
  1. H. K. Zhang, “Democratizing LED-Based Photoacoustic Imaging with Adaptive Beamforming and Deep Convolutional Neural Network”, LED-based Biomedical Photoacoustic Imaging, Edited by Mithun Kuniyil Ajith Singh, Springer, 2020.
Journal Articles
  1. Y. Wu, H. K. Zhang, J. Kang, E. M. Boctor, “An Economic Photoacoustic Imaging Platform Using Automatic Laser Synchronization and Inverse Beamforming”, Ultrasonics, 103, 106098, 2020.
Conference Proceedings
  1. S. Gao, R. Tsumura, D. P. Vang, K. Bisland, K. Xu, Y. Tsunoi, H. K. Zhang, “Compact and Low-Cost Acoustic-Resolution Photoacoustic Microscopy Based on Delta Configuration Actuator”, Proc. IEEE (International Ultrasonics Symposium), 2020.
  2. R. Tsumura, H. K. Zhang, “Forward-Viewing Ultrasound Imaging with Concentric-Ring Arrays for Registration-Free Needle Intervention”, Proc. IEEE (International Ultrasonics Symposium), 2020.
  3. R. Tsumura, Y. Tang, H. K. Zhang, “Reflector-based Transrectal 3D Ultrasound Imaging System”, Proc. IEEE (International Ultrasonics Symposium), 2020.
  4. K. Bimbraw, X. Ma, Z. Zhang, H. K. Zhang, “Augmented Reality-Based Lung Ultrasound Scanning Guidance”, MICCAI Workshop, 2020
  5. J. Kaminski, K. Rafatzand, H. K. Zhang, “Robot-Assisted Ultrasound Imaging for Repetitive Follow-up Assessment of Thyroid Disease”, Proc. SPIE (Medical Imaging), 2020.
  6. R. Tsumura, D. P. Vang, N. Hata, H. K. Zhang, “Ring-Arrayed Forward-Viewing Ultrasound Imaging System: A Feasibility Study”, Proc. SPIE (Medical Imaging), 2020.
Conference Abstracts
  1. H. K. Zhang, “Multiscale Spectroscopic Photoacoustic Image Instrumentation for Prostate Cancer Detection”, The 11th National Image Guided Therapy Workshop, 2020.
  2. Y. Tang, R. Tsumura, H. K. Zhang, “Co-Axial Three-Dimensional Photoacoustic Imaging Based on Double-Reflector and Modified Elevational Synthetic Aperture Focusing”, IEEE International Ultrasonics Symposium, 2020.
  3. J. Kaminski, H. K. Zhang, “Reproducible Thyroid Ultrasound Procedure Enabled by Robot-Assisted Scanning”, IEEE International Ultrasonics Symposium, 2020.


Journal Articles
  1. Jeeun Kang, Haichong K. Zhang, Shilpa D. Kadam, Julie Fedorko, Heather Valentine, Adarsha P. Malla, Ping Yan, Maged Harraz, Jin U. Kang, Arman Rahmim, Albert Gjedde, Leslie M. Loew, Dean F. Wong, Emad M. Boctor, “Transcranial recording of electrophysiological neural activity in the rodent brain in vivo using functional photoacoustic imaging of near-infrared voltage-sensitive dye”, Frontiers in Neuroscience, 13, 579, Open Access.
Conference Proceedings
  1. Keshuai Xu, Younsu Kim, Emad M. Boctor, Haichong K. Zhang, “Enabling low-cost point-of-care ultrasound imaging system using single element transducer and delta configuration actuator”, Proc. SPIE (Medical Imaging), 2019.
Conference Abstracts
  1. Yixuan Wu, Jeeun Kang, Haichong K. Zhang, Martin G. Pomper, Emad M. Boctor, “Effective multi-spectral photoacoustic imaging of prostate-specific membrane antigen (PSMA) targeted agent for aggressive prostate cancer detection”, IEEE International Ultrasonic Symposium, 2019.
  2. Raissa Mulombe, Doua P. Vang, Ryosuke Tsumura, Jonian Grosha, Paige Waligora, Marsha W. Rolle, Haichong K. Zhang, “The Ultrasound Bioreactor System Image-Based Compliance Analysis or Tissue Engineered Blood Vessel Rings”, BMES, 2019.
  3. Zachery H. Shropshire, Haichong K. Zhang, Gregory S. Fischer, Christopher J. Nycz, “Relating Sonomyographic Images with EMG and Motion Capture for User Control of Prosthetics and Orthotics”, BMES, 2019.
  4. Paige Waligora, Jonian Grosha, Raissa Mulombe, Doua Vang, Haichong Zhang, Marsha Rolle, “Optimizing a Protocol for Creating a Biological Phantom for use in Validating an Ultrasound System”, BMES, 2019.
  5. Jakub T. Kaminski, Haichong K. Zhang, “Autonomous robotic ultrasound scanning with six-degree-of-freedom force feedback control”, UITC, 2019.
  6. Keshuai Xu, Christian A. Hernandez, Younsu Kim, Haichong K. Zhang, Emad M. Boctor, “Modular ultra sound for needle guidance: a hands-free approach”, Ultrasound Imaging and Tissue Characterization Conference, 2019.
  7. Jeeun Kang, Yixuan Wu, Ala Lisok, Haichong K. Zhang, Martin G. Pomper, Sangeeta Ray, Emad M. Boctor, “Contrast-enhanced spectroscopic photoacoustic imaging of prostate cancer using fluorescence-quenching prostate-specific membrane antigen (PSMA)-targeted contrast agent”, Ultrasound Imaging and Tissue Characterization Conference, 2019.

Previous publications (- 2018)

  • H. K. Zhang, A. Cheng, Y. Kim, Q. Ma, G. S. Chirikjian, E. M. Boctor, “A Phantom with Multiple Active Points for Ultrasound Calibration”, in Journal of Medical Imaging, 5(4), 045001, 2018, Link.
  • E. M. A. Anas, H. K. Zhang, J. Kang, E. M. Boctor, “Enabling Fast and High Quality LED Photoacoustic Imaging: A Recurrent Neural Networks Based Approach”, in Biomedical Optics Express, 9(8), 3852, 2018, Open Access.
  • J. Kang, E. M. Boctor, S. Adams, E. Kulikowicz, H. K. Zhang, K. Raymond, and E. Graham, “Validation of Noninvasive Photoacoustic Measurements of Sagittal Sinus Oxyhemoglobin Saturation in Hypoxic Neonatal Piglets”, in Journal of Applied Physiology, 125(4), 983-989, 2018, Link.
  • [H. K. Zhang, Y. Chen], J. Kang, A. Lisok, I. Minn, [M. G. Pomper, and Emad M. Boctor], “Prostate Specific Membrane Antigen (PSMA)-Targeted Photoacoustic Imaging of Prostate Cancer In Vivo”, in Journal of Biophotonics, e201800021, 2018, Link.
  • H. K. Zhang, Y. Kim, M. Lin, M. Paredes, K. Kannan, A. Moghekar, N. Durr, E. M. Boctor, “Toward dynamic lumbar puncture guidance using needle-based single element ultrasound imaging”, in Journal of Medical Imaging, 5(2), 021224, 2018, Link.
  • A. Cheng, Y. Kim, Y. Itsarachaiyot, H. K. Zhang, C. R. Weiss, R. H. Taylor, E. M. Boctor, “Photoacoustic-based catheter tracking: simulation, phantom, and in vivo studies”, in Journal of Medical Imaging, 5(2), 021223, 2018, Link.
  • A. Cheng, X. Guo, H. K. Zhang, H. J. Kang, R. Etienne-Cummings, and E. M. Boctor, “Active phantoms: a new paradigm for ultrasound calibration using phantom feedback”, in Journal of Medical Imaging, 4(3), 035001, 2017, Link.
  • [H. K. Zhang, P. Yan], J. Kang, D. S. Abou, H. N. D. Le, A. K. Jha, D. L. J. Thorek, J. U. Kang, A. Rahmim, D. F. Wong, [Emad M. Boctor, Leslie M. Loew], “Listening to membrane potential: Photoacoustic voltage sensitive dye recording”, in Journal of Biomedical Optics, 22(4), 045006, 2017, PDF.
  • T.-Y. Fang, H. K. Zhang, R. Finocchi, R. H. Taylor, E. M. Boctor, “Force Assisted Ultrasound Imaging System through Dual Force Sensing and Admittance Robot Control”, in International Journal for Computer Assisted Radiology and Surgery (IJCARS), 12(6), 983-991, 2017, Link.
  • H. K. Zhang, M. Bell, X. Guo, H. J. Kang, Emad M. Boctor, “Synthetic-aperture based photoacoustic re-beamforming (SPARE) approach using beamformed ultrasound data”, in Biomedical Optics Express, 7(8), 3056-3068, 2016, Open Access.
  • H. K. Zhang, A. Cheng, N. Bottenus, X. Guo, G. E. Trahey, Emad M. Boctor, “Synthetic Tracked Aperture Ultrasound (STRATUS) Imaging: Design, Simulation, and Experimental Evaluation”, in Journal of Medical Imaging, 3(2), 027001, 2016, Open Access.
  • N. Bottenus, W. Long, H. K. Zhang, M. Jakovljevic, D. P. Bradway, E. M. Boctor, G. E. Trahey, “Feasibility of Swept Synthetic Aperture Ultrasound Imaging”, in IEEE Transactions on Medical Imaging, 35(7), 1676-1685, 2016.
  • F. Aalamifar, A. Cheng, Y. Kim, X. Hu, H. K. Zhang, X. Guo, E. M. Boctor, “Robot Assisted Automatic Ultrasound Calibration”, in International Journal of Computer Assisted Radiology and Surgery (IJCARS), 11(10), 1821-1829, 2016.
  • H. K. Zhang, K. Kondo, M. Yamakawa, T. Tsuyoshi, “Coded Excitation Using Periodic and Unipolar M-sequences for Photoacoustic Imaging and Flow Measurement”, in Optics Express, 24(1), 17-29, 2016, Open Access.
  • H. Zhang, K. Kondo, M. Yamakawa, T. Tsuyoshi, “Simultaneous Multispectral Coded Excitation Using Gold Codes for Photoacoustic Imaging”, in Jpn. Journal of Applied Physics, 51 (7), 07GF03, 2012, PDF.