Downstream Principles and Techniques

Downstream Training

Virtual delivery available!

Email  Catherine Bouthillier

UPCOMING CERTIFICATE PROGRAMS: In-person TBD, contact Catherine Bouthillier to discuss virtual delivery!

Improve your basic skills in separation and purification of bio-manufactured products with both single-use and stainless equipment. This training includes theoretical background information on cell harvest and clarification, TFF, and chromatography, including column packing. You will also develop a better understanding of the various protein characteristics and how they affect the purification process, how resins are selected, and how a purification process is developed.

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There are no academic prerequisites for this program

Key Learning Objectives

  • Understand the principles of centrifugation and how cell harvesting and clarification is completed
  • Understand the principles and applications for depth filtration
  • Understand how protein characteristics facilitate the purification process
  • Become familiar with the different types of chromatographic processes and the principles behind each type
  • Identify the components of a chromatography system and their functions
  • Perform column packing and peak evaluation
  • Identify the components of a TFF system and their functions
  • Understand how viruses are inactivated and removed
  • Understand how a purification process is developed

Benefits of this interactive training

  • Increase your knowledge of the operation, maintenance and troubleshooting of centrifuges, filtration systems, TFF systems and Chromatography systems
  • Decrease the number of process excursions and deviations due to operator error
  • Reduce the time required to become a subject matter expert in your field
  • Become cross-trained in purification procedures to diversify your skill set