Publications

White, H, Kamara, V, Gorski, V, Busby, M, Albrecht, DR. Automated Multimodal Stimulation and Simultaneous Neuronal Recording from Multiple Small Organisms. J. Vis. Exp. (193), e65042, doi:10.3791/65042 (2023).

 

Lagoy, RC, Larsen, E, Lawler, D, White, H, Albrecht, DR. Microfluidic devices for behavioral analysis, microscopy, and neuronal imaging in Caenorhabditis elegans. Methods in Molecular Biology. 2468, 293-318 (2022).

 

 

 

Lawler, DE., & Albrecht, DR. Monitoring neural activity during sleep/wake events in adult C. elegans by automated sleep detection and stimulation. STAR protocols, 3(3), 101532.  (2022).

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Lawler DE, Chew YL, Hawk JD, Aljobeh A, Schafer WR, Albrecht DR. Sleep analysis in adult C. elegans reveals state-dependent alteration of neural and behavioral responses. Journal of Neuroscience. 2021 Mar 3;41(9):1892-907.

 Figure 1 from Sleep Analysis in Adult C. elegans Reveals State-Dependent Alteration of Neural and Behavioral Responses
 

Han X, Su Y, White HA, O’Neill KM, Morgan NY, Christensen R, Potarazu D, Vishwasrao HD, Xu S, Sun Y, Huang S, Moyle MW, Dai Q, Pommier Y, Giniger E, Albrecht DR, Probst R, Shroff H. A polymer gel index-matched to water enables diverse applications in fluorescence microscopy. Lab Chip 21(8):1549-1562 (2021).

 Figure 3 from A polymer gel index-matched to water enables diverse applications in fluorescence microscopy
Lagoy RC, Larsen E, Albrecht DR, Automated Functional Screening for Modulators of Optogenetically Activated Neural Responses in Living Organisms. In Channelrhodopsin 2021 (pp. 221-233). Humana, New York, NY.

 

 

Jang S, Xuan Z, Lagoy RC, Jawerth LM, Gonzalez IJ, Singh M, Prashad S, Kim HS, Patel A, Albrecht DR, Hyman AA, Colón-Ramos DA. Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo. Biophys J. 120(7):1170-1186, doi: 10.1016/j.bpj.2020.08.002 (2021).

 Figure 3 from Phosphofructokinase relocalizes into subcellular compartments with liquid-like properties in vivo

 

 

 

Montoya NV, Peterson R, Ornell KJ, Albrecht DR, Coburn JM. Silk Particle Production Based on silk/PVA Phase Separation Using a Microfabricated Co-flow Device. Molecules. 2020 Feb 17;25(4):890.

 Figure 8 from Silk Particle Production Based on silk/PVA Phase Separation Using a Microfabricated Co-flow Device
Lagoy R, Kim H, Mello CC, Albrecht DR(§). A C. elegans model for the rare human channelopathy, Timothy syndrome type 1. microPublication Biology (2018), doi: 10.17912/micropub.biology.000081.

 

Burnett K, Edsinger E, and Albrecht DR(§). Rapid and gentle hydrogel encapsulation of living organisms enables long-term microscopy over multiple hours Communications Biology (2018).

bioRXiv preprint, http://dx.doi.org/10.1101/194282

 

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Lagoy RC and Albrecht DR(§). Automated fluid delivery from multiwell plates to microfluidic devices for high-throughput experiments and microscopy Scientific Reports 8(1), 6217 (2018).

  

 

 

Fagan KA, Luo J, Lagoy RC, Schroeder FC, Albrecht DR, and Portman DS. A Single-Neuron Chemosensory Switch Determines the Valence of a Sexually Dimorphic Sensory Behavior Current Biology 28(6), 902-914. (2018)

  

 

 

Reilly DK, Lawler D, Albrecht DR(§), and Srinivasan J. Using an adapted microfluidic olfactory chip for the imaging of neuronal activity in response to pheromones in male C. elegans head neurons J Vis Exp (2017).

Figure 2: A male-adapted microfluidic olfactory chip.

Figure 3 from “Using an Adapted Microfluidic Olfactory Chip for the Imaging of Neuronal Activity in Response to Pheromones in Male C. Elegans Head Neurons”, free on PubMed

 

Benesch-Lee F, Lazaro Guevara JM, and Albrecht DR. Multilayer photolithography with manual photomask alignment. Chips & Tips (2017)

  
Hansen K, Favreau JT, Gershlak JR, Laflamme MA, Albrecht DR, and Gaudette GR. Optical Method to Quantify Mechanical Contraction and Calcium Transients of Human Pluripotent Stem Cell Derived Cardiomyocytes Tissue Engineering Part C: Methods (2017), doi: 10.1089/ten.TEC.2017.0190 Fig

 

Shendi D, Albrecht DR, Jain A. Anti-Fas Conjugated Hyaluronic Acid Microsphere Gels for Neural Stem Cell Delivery. Journal of Biomedical Materials Research: Part A 105(2): 608-618 (2017).

  

 

 

Larsch J, Flavell SW, Liu Q, Gordus A, Albrecht DR, Bargmann CI. A Circuit for Gradient Climbing in C. elegans Chemotaxis. Cell Reports 12(11):1748-60. doi: 10.1016/j.celrep.2015.08.032 (2015).

 

 

Lagoy RC and Albrecht DR. Microfluidic Devices for Behavioral Analysis, Microscopy, and Neuronal Imaging in Caenorhabditis elegans. Methods Mol Biol. 1327:159-79. doi: 10.1007/978-1-4939-2842-2_12. (2015).

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Larsch J, Ventimiglia D, Bargmann CI, and Albrecht DR. High-throughput imaging of neuronal activity in C. elegans. Proc Natl Acad Sci 110(45):E4266-E4273 (2013).

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Flavell SW, Pokala N, Macosko EZ, Albrecht DR, Larsch J, Bargmann, CI. Serotonin and the Neuropeptide PDF Initiate and Extend Opposing Behavioral States in C. elegans. Cell 154(5): 1023–1035 (2013).

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Garrison JL, Macosko EZ, Bernstein S, Albrecht DR, Pokala NP, Bargmann CI. An ancient role for oxytocin/vasopressin-related peptides in reproductive behavior. Science 338(7):540-543 (2012).

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Albrecht DR and Bargmann CI. High-content behavioral analysis of Caenorhabditis elegans in precise spatiotemporal chemical environments. Nature Methods 8(7):599-605 (2011).

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Chalasani SH, Kato S, Albrecht DR, Nakagawa T, Abbott LF, and Bargmann CI. Neuropeptide feedback modifies odor-evoked dynamics in olfactory neurons. Nature Neuroscience 13(5):615-21 (2010).

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Albrecht DR, Underhill GH, Resnikoff J, Mendelson A, Bhatia SN, and Shah JV. Microfluidics-integrated time-lapse imaging for analysis of cellular dynamics. Integrative Biology 2(5-6):278-87 (2010). publication 8 photo
Albrecht DR, Underhill GH, Mendelson A, and Bhatia SN. Multiphase Electropatterning of Cells and Biomaterials. Lab Chip 7:702-9 (2007). publication 7 photo

 

 

 

 

Chen AA, Tsang VL, Albrecht DR, and Bhatia SN. 3-D Fabrication technology for tissue engineering. BioMEMS and Biomedical Nanotechnology 7:23-38 (2007).

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Underhill GH, Chen AA, Albrecht DR, and Bhatia SN. Assessment of Hepatocellular Function within PEG Hydrogels. Biomaterials 28:256-270 (2006).

 Figure 6 from Assessment of hepatocellular function within PEG hydrogels

 

Albrecht DR, Underhill GH, Wassermann TB, Sah RL, and Bhatia SN. Probing the Role of Multicellular Organization in Three-Dimensional Microenvironments. Nature Methods 3(5):369-375 (2006).

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Albrecht DR, Liu Tsang V, Sah RL, and Bhatia SN. Photo-and electro-patterning of Hydrogel-Encapsulated Living Cell Arrays. Lab Chip 5(1):111-118 (2005).

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Albrecht DR, Sah RL, and Bhatia SN. Geometric And Material Determinants Of Patterning Efficiency By Dielectrophoresis. Biophys. J. 87(4):2131-2147 (2004).

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Fridén J, Albrecht DR, and Lieber RL. Biomechanical Analysis of the Brachioradialis as a Donor in Tendon Transfer. Clin. Orthop. Rel. Res. 383:152-161 (2001).