Data Mining and Applications for Pharmacovigilance

Authors

Katie Elizabeth Brochu, Nicholas Anthony Diaz, Sadie Grace Gauthier, Erik I. Nadel

Sponsor

Food and Drug Administration

Advisors

Fred J. Looft, Brigitte Servatius

Term

October – December 2015

Project Outcomes

Final Report

Abstract

In order to ensure the safety and efficacy of post-market pharmaceutical products, the United States Food and Drug Administration relies on its pharmacovigilance efforts and input from the general public. The FDA receives submissions of adverse event reports from patients, health care practitioners and manufacturers. The FDA has started looking to the field of data mining to automate the search for safety signals. A training manual was created to introduce FDA employees to the concepts and applications of data mining techniques in pharmacovigilance.